Characterization of Murine Cardiac Cholinergic Innervation and its Remodeling
نویسندگان
چکیده
s:Hoover DB, Hoard JL, Mabe AM, Dodi EK. Colocalization ofcholinergic and noradrenergic markers in mouse intracardiacneurons and nerve fibers. Program No. 305.5. 2005 AbstractViewer/ Itinerary Planner. Washington, DC: Society forNeuroscience, 2005. OnlineHoard JL, Mabe AM, Wondergem R, Hoover DB. Coculture ofmouse intrinsic cardiac neurons. Program No. 29.10. 2006Neuroscience Meeting Planner. Atlanta, GA: Society forNeuroscience, 2006. Online
منابع مشابه
Heart‐Specific Overexpression of Choline Acetyltransferase Gene Protects Murine Heart Against Ischemia Through Hypoxia‐Inducible Factor‐1α–Related Defense Mechanisms
BACKGROUND Murine and human ventricular cardiomyocytes rich in acetylcholine (Ach) receptors are poorly innervated by the vagus, compared with whole ventricular innervation by the adrenergic nerve. However, vagal nerve stimulation produces a favorable outcome even in the murine heart, despite relatively low ventricular cholinergic nerve density. Such a mismatch and missing link suggest the exis...
متن کاملDisruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias
The parasympathetic nervous system plays an important role in the pathophysiology of atrial fibrillation. Catheter ablation, a minimally invasive procedure deactivating abnormal firing cardiac tissue, is increasingly becoming the therapy of choice for atrial fibrillation. This is inevitably associated with the obliteration of cardiac cholinergic neurons. However, the impact on ventricular elect...
متن کاملHeart-Specific Overexpression of Choline Acetyltransferase Gene Protects Murine Heart Against Ischemia Through Hypoxia-Inducible Factor-1a–Related Defense Mechanisms
Background-—Murine and human ventricular cardiomyocytes rich in acetylcholine (Ach) receptors are poorly innervated by the vagus, compared with whole ventricular innervation by the adrenergic nerve. However, vagal nerve stimulation produces a favorable outcome even in the murine heart, despite relatively low ventricular cholinergic nerve density. Such a mismatch and missing link suggest the exi...
متن کاملActivity-Dependent Changes in Cholinergic Innervation of the Mouse Olfactory Bulb
The interplay between olfactory activity and cholinergic modulation remains to be fully understood. This report examines the pattern of cholinergic innervation throughout the murine main olfactory bulb across different developmental stages and in naris-occluded animals. To visualize the pattern of cholinergic innervation, we used a transgenic mouse model, which expresses a fusion of the microtu...
متن کاملThe Effect of Cardiac Rehabilitation on Left Ventricular Remodeling in Men and Women Patients with Coronary Artery Disease
Objective: Left ventricular (LV) remodeling is associated with increased morbidity and mortality therefore, interventions that halt or reverse ventricular remodeling are expected to prevent these clinical outcomes. The aim of the study was to assess the effects of cardiac rehabilitation program on cardiac remodeling process in patients with coronary artery disease and then compare the results b...
متن کامل